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Updated on 22.02.2007
Completed Clinical Trials
CYCAZAREM (cyclophosphamide versus azathioprine for remission in generalised vasculitis) was completed and published in The New England Journal of Medicine in 2003.
SOLUTION (anti-thymocyte globulin for refractory vasculitis) was completed and published in Kidney International in 2004.
NORAM (methotrexate versus cyclophosphamide for 'early systemic' disease) was completed and published in Arthritis & Rheumatism in 2005.
CHUSPAN (Churg-Strauss and polyarteritis nodosa) was completed in 2005. Its four different protocols included either Churg-Strauss syndrome or polyarteritis nodosa (PAN) plus microscopic polyangiitis (MPA) both either with good and poor prognosis. The results of PAN/MPA with bad prognosis were published in Arthritis & Rheumatism in 2003. Futher reports are in preparation.
CYCLOPS (daily oral versus pulse cyclophosphamide for renal vasculitis) is completed and will be published soon.
MEPEX (methyl prednisolone or plasma exchange for severe renal vasculitis) is completed and will soon be published. The results have been presented to the American Society of Nephrology (abstract) and are summerised in a recent review.